Debilitate counter: All the debuffs and status cards that get thrown at the player here are brutal, however, multiple stacks of Artifact can help prevent some of them and the Medical Kit shop relic can be used to exhaust the status cards.RELATED: Slay The Spire: The Best Cards For The Defect, Ranked Attack Counters Invincible acknowledgment: No way around this one, though since the Corrupt Heart has 750 HP, the 300 damage cap per turn means that the fastest that the player can slay the great organ is 3 turns, which isn't that restrictive even for the more aggressive strategies.Beat of Death counter: the Tungsten Rod rare relic & the After Image green power card totally negate the beat of death's effect by decreasing all incoming damage by 1 (Tungsten Rod) or gaining 1 block (before the effect of Beat of Death occurs) every time a card is played (After Image).5th Time & onwards: Increases the Corrupt Heart's Strength by 50.4th Time: Increases the Corrupt Heart's Strength by 10.3rd Time: Applies Painful Stabs to the player, which spawns a Wound card in their deck each time they take unblocked damage.2nd Time: Beat of Death increases by 1 stack, meaning that its effect is now doubled so that the player takes 2 damage every time they play a card.1st Time: Gives the boss +2 Artifact (each stack of Artifact prevents 1 debuff).

Furthermore, each time this Buff is used, it removes all Strength debuffs from the Corrupt Heart as well as gives the boss +2 Strength. Here are its effects that differ for the first 5 times it is used following the 5th use, the effects do not change again. While the Buff counts as an Attack, it is quite complex and warrants greater attention. RELATED: Slay The Spire: The Best Cards For The Ironclad, Ranked Buff Debilitate: Applies 2 Vulnerable, 2 Frail, and 2 Weak while also shuffling 1 Dazed, 1 Slimed, 1 Wound, 1 Burn, and 1 Void card into the player's draw pile.

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